Transportation From the Airport
Airport Guide (pdf)
Prague's public transport system offers you the cheapest way to get from the airport to the city center and vice versa.
Bus no. 119 operates between the Dejvická Metro Station and terminal-North of Prague-Ruzyně Airport (Stop-Nove Letisti). Bus 119 runs every 20 - 40 minutes between the hours of 4:00 and 24:00. This trip should take about 30-40 minutes including waiting-time.
Bus no. 100 will take you from Ruzyně Airport to Zlicin Metro Station (and back) in just 13 minutes. The bus is adapted to carry additional baggage. On working days, in the morning and afternoon, the bus operates in 15 minute intervals, otherwise the interval is 30 minutes.
Before you get on a bus, you have to buy a 12-crown ticket, available from vending machines or newsagents.
Any taxi will drive you to the airport from the city center. In the opposite direction, there are taxis marked "Airport" on their roofs. The price consists of a 25-crown boarding fee and the charge should be 17 crowns/km. You should not pay more than 500 crowns for the entire trip.
Minibus -- CEDAZ People Carrier
You may also use a shuttle service between the airport and the city center. Minibuses will go from the Airport Ruzyně to Dejvická Metro Station, stop downtown at Namisti Republiky Metro Station, at the CSA City Travel Center (very near to the Renaissance and Marriot Hotels) and back. VW transporter minibuses are for 6 passengers. Price for a single trip is 90 crowns per passenger with 1 luggage. They are easy to find, walk a few meters beyond the standard taxis that are right outside the arrivals exit.
Note that the CEDAZ Company also offers transportation to any place in Prague (hotel, private accommodation, etc.), in the Czech Republic, and in Europe by way of their Volkswagen vans.